In October 2021, its application in Ecuador Dosage Strength against Covid-19. For this process, biological Pfizer Y. AstragenecaIndependently Formula Previously applied.

That is, if the person receives a dose of Pfizer (Messenger RNA or MRNA) or both Synovac (Inactivated virus), is done with booster Astrageneca.

Guidelines for Vaccination The strengthening of the Ministry of Health indicates that the results of the clinical study show that Different schemes These include the mRNA-type vaccine (Pfizer-BionTech) and inactivated viruses, which are later developed with the adenovirus vector vaccine (AstraZeneca), producing a stronger cellular and humoral response than that. Similar schemes.

This adjustment also applies The second booster. The vaccine, which has been administered since April 1, 2022, is administered to people over the age of 50 and to the preferred population thereafter. Five months from the third dose.
Documents Ministry of Health Recommends that if a person gets Pfizer in the first booster, it can be placed in the second Astrageneca Or a Vaccine Of the same brand.

Similarly, when AstraZeneca is applied, the same or Pfizer is recommended as a second booster; And it is recommended if you are getting Synovac AstraZeneca or Pfizer. According to all Presence Of the vaccine

Good immune response

Related, Washington CardinasA professor at Escuela Politécnica del Litoral (Espol) noted that a study published on an international scale showed that the immune response was similar or better with mixed schemes.

The expert mentions one Research, Published in June 2021; There, it was reported that the combination of the first dose of AstraZeneca and the second dose of Pfizer produced more antibodies and T cells (immune cells that kill germs) than the two uses of AstraZeneca.

Also, there was more to use first Pfizer and then AstraZeneca Useful To use twice British vaccineAlthough not as effective as using them in reverse order.

If the shot is low in the case of the booster Effective More than any other, these mixed schemes can ensure that those who have received less effective doses can take one Strengthening With a more efficient

A more recent study from Oxford University found that a The third dose With a vaccine produced by AstraZeneca, Pfizer-BioNTech or Johnson & Johnson Level From Antibodies Who had previously received two doses of Sinovak.

Last December, the European Medicine Agency (EMA) and the European Center for Disease Prevention and Control (ECDC) and Dose adjustment approval. “A heterologous booster seems to be better or better at immune response than a homogeneous booster,” they said.

Reducing infections

Biotechnology expert, Jhomamara Batista explains that Zhak Either in combination with the vaccine or at the same time because the purpose of the enhancement is to provide the organism with the process of reproduction. Antibodies.

With this he mentions Two doses The immune system has protection against Covid-19, but it is reduced in four to six months, so it is necessary. Dwell A third dose, the same as the previous two or the other.

Bautista recalls that being in an epidemic is important to achieve Community protection. He noted that immunization reduces the rate of infection because you have higher levels of antibodies and are less likely to become infected after being vaccinated and are less likely to be infected with the virus in other people.


In the United States, three doses of Pfizer / BioNTech compound will be given to children aged 12 to 15 years.

Children aged 5 to 11 with immune system deficiency will also be able to access the third dose.

Children ages 5 to 11 began receiving their first anti-Covid-19 injection last November.

In Ecuador, the Ministry of Health has not yet approved the application to strengthen the anticoagulant-19 vaccine for children aged 5 to 12 years.

Vaccination of this group in Ecuador began in October 2021. The Chinese synovac vaccine is administered.

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